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Bioshock Hints
Splicer Group Combat Tips
1 of 3: If you hacked the RPG turret earlier, shoot one of the splicers with a single pistol bullet, then drop down to the floor behind the turret while it toasts them for you.
2 of 3: Or hit one of them with the Enrage plasmid.
3 of 3: Or use your new grenade launcher to launch a grenade into the midst of the splicers. One well-placed frag grenade will kill all of them at once.