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Bioshock 2 Hints
Activate the Quarantine Chamber.
1 of 6: Soon after you activate the controls to the left of the quarantine chamber's door, two big sisters will drop into the room and attack you.
2 of 6: You'll want to prepare for that ahead of time by setting some traps up where they're going to drop down.
3 of 6: They'll both drop to spots just a little NE of the quarantine chamber's door, near a chalk X that's on the floor.
4 of 6: Use Telekinesis to move the room's five explosive items to a spot next to the chalk X, then set five prox mines in a tight cluster around them.
5 of 6: Use the Gene Bank machine to splice in the Drill Power, Drill Power 2, Freezing Drill, and Drill Vampire tonics.
6 of 6: Use the hack tool to deploy three mini-turrets a ways east of your prox mine trap, then go activate the door controls right after quicksaving.