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Bioshock 2 Hints
Splicer Combat Tips
1 of 4: The splicers won't attack the big daddy unless you use the Hypnotize plasmid on them.
2 of 4: Stay as far back as you can and shoot the splicers with the rivet gun or speargun, being careful not to hit the big daddy.
3 of 4: After all the leadheads are dead, move toward their area slowly, watching for a door to open in the back left corner.
4 of 4: A brute splicer will come through that door, so be ready to research and kill him.