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Bioshock 2 Hints
Thaw the Frozen Door.
1 of 10: On your way back past the Vita-Chamber, watch for a thuggish splicer hiding among the mannequins on the left.
2 of 10: Head-shot him with a rivet before he starts moving, then go down the curvy hallway and look near the door for an iced-over passage.
3 of 10: Now that you have Incinerate!, you can melt the ice and explore the area beyond it.
4 of 10: After you pass your hacked SMG turret and go through a door, get out the Incinerate! plasmid, load heavy rivets into the rivet gun, and then get out the machine gun.
5 of 10: When you approach the next door, a big sister will pull you into the museum and attack you, which gets you the "Kill the Big Sister" goal.
6 of 10: After you finish it, loot the big sister to get some items -- including 40 units of ADAM -- then check the vending machines for anything you need to buy.
7 of 10: Also, return to the Hall of the Future's defrosted side area to restock on heavy rivets and possibly buy something else from the garden machine. (Armored Shell is highly recommended.)
8 of 10: When you're done looking around, go through the door at the south end of the museum's upper floor to return to the museum entrance area.
9 of 10: South of it, look near the vending machine for some ice you can melt. Doing so allows you to get an EVE hypo, an audio diary, two boxes of .50 caliber rounds, and a money clip.
10 of 10: Go through the next two doors to get back to the train station, then go up to the front of the train and use Incinerate! to melt the large chunks of ice that are blocking the track.