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Vampire the Masquerade: Bloodlines Hints
Defense
1 of 3: A useful, but not critical, feat. You'll want to have at least 5 in this eventually so you don't get hit all the time by weak enemies, and it is nice to have a lot of it against bosses, since it's tough to soak their damage.
2 of 3: You can also use block to increase Defense by a number equal to your Dexterity by holding down TAB. This can be made more effective by using Bloodbuff to boost your Dexterity to 5.
3 of 3: Defense is, for some reason, based on Wits, so Vampires who get the Hacking feat will also get some easy Defense. Doesn't make too much sense, but it's handy for making enemies whiff when you're a stealthy character. As with most feats, there is an opportunity to increase this through a book.