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Diablo II Hints
How do I solve the "Sisters to the Slaughter" quest?
1 of 10: This is the last quest of the chapter, so be sure to clean out any areas you want before doing this quest. The extra skill points and stats won't hurt either.
2 of 10: Talk to Deckard Cain to receive this quest.
3 of 10: He will send you to kill Anderial.
4 of 10: You will have to go a long ways to find her, starting in the Monastery, going down through the Jail Levels, and eventually to the Catacombs.