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Fallout: New Vegas Game Add-Ons (DLC) Hints
Is there another way to get it open?
1 of 4: There's a key to it on the second floor.
2 of 4: If you didn't disable the security hologram, switch it to patrolling the first floor so you can explore the second floor.
3 of 4: Enter the office that's about halfway down the east wall of the second floor.
4 of 4: Loot the desk to get the key, then optionally use the terminal on the desk to get the vending machine code for med-x. (Note that the mentats code is on the wooden shelves in the southern-most east-side office.)