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Fallout 3 Hints
Enslave Red from Big Town.
1 of 8: Red is the girl in Big Town (location 10 on the Zone 5 Map) who's wearing a red jumpsuit and a red bandana.
2 of 8: That is, she's in Big Town if you've already rescued her on the "Big Trouble in Big Town" misc. quest.
3 of 8: You could enslave her during that quest without returning her to Big Town, but it's best to completely finish that quest before working on this objective.
4 of 8: If you want to avoid turning all of Big Town hostile, you'll have to wait until Red is alone in an area (like her clinic) before you use the mesmetron on her.
5 of 8: Or you can zap her at any time and quickly run away from town to avoid getting killed. The town residents will calm down after three game days have passed.
6 of 8: In any case, talk to Red as soon as you mez her.
7 of 8: Choose the option that lets you rob her of her few items, then get her to put on the slave collar and run for Paradise Falls.
8 of 8: Make a quick getaway if you need to, then fast-travel back to Paradise Falls and talk to Grouse to get your reward and another slave collar.