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Fallout 3 Hints
The Runaway Slave
1 of 10: Go to Rivet City (location 64 on the Zone 9 Map) and board the ship.
3 of 10: Say you won't hurt her, and she'll admit that she's a runaway slave.
4 of 10: She's afraid the slaver named Sister, who currently resides in Rivet City, will find out about her and re-enslave her.
5 of 10: If you want to gain karma from this, you should give her 25 caps to buy herself a pistol with.
6 of 10: Otherwise, say you'll think about it or that you refuse to get involved, then go find Sister.
7 of 10: He can often be found in the Upper Deck area, in his room or in the Weatherly Hotel's main office.
8 of 10: Talk to him however many times you have to so you can tell him about Mei Wong.
9 of 10: That'll lose you some karma, and you can lose even more if you go find Mei Wong and tell her that you reported her to Sister.
10 of 10: As an alternative, you could give her the 25 caps for a gun now to regain some lost karma. Or you could just do nothing and wait for her to be taken away by slavers.