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Half-Life 2: Episode One Hints
Zombine and Headcrab Tips
1 of 6: You could use the shotgun to shoot the grenade out of the zombine's hand or the gravity gun to grab it and throw it, then retreat and shotgun it in the head (or let Alyx take it down).
2 of 6: But it's better to open the doors in such a way that the zombine doesn't see you and charge you with its grenade.
3 of 6: After removing the doors' wooden beam, stand or crouch in the corner to the right of them after moving the supply crate and cement blocks out of the way.
4 of 6: You can open the doors while standing there without having to move.
5 of 6: Do so, then stay in that exact spot until the zombine's grenade blows it up inside the room. It and at least one of the headcrabs in there should be killed by the explosion.
6 of 6: The other headcrab probably leaped at Alyx, thereby avoiding the explosion, so help her kill it.