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Nancy Drew 22: Trail of the Twister Hints
What's the difference between the Junior and Senior games?
As usual, Junior detectives get easier versions of some puzzles. In addition, Juniors can call the Hardy boys with questions; Seniors can call just to talk, but they don't get to ask outright questions. And then there's that lovely checklist, which helps you keep track of the chores you haven't done yet.
If you're playing as a Senior detective, you might need to keep a pad of paper nearby and jot down the chores as you get them; it's pretty hard to keep track of them otherwise.