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The Elder Scrolls IV: Oblivion Hints
Five Leaves of Nightshade
1 of 5: If you've gone to ingredient sellers to find your garlic and/or bloodgrass, you've probably already found all the nightshade you need (if you thought to check their inventories for it).
2 of 5: For instance, Ogier Georick in the IC Market District's "The Main Ingredient" has four non-random nightshade leaves to sell. That's almost all you need!
3 of 5: If you've done enough Mages Guild quests to gain full access to the Arcane University, you can find several nightshade plants to harvest from in the university's back half.
4 of 5: Otherwise, look in the various Mages Guilds to find some free samples.
5 of 5: There's one on top of a book on a table in the NW bedroom in the Anvil Mages Guild Library, another on a small stool near the NW corner of the Anvil Mages Guild Living Quarters, and three on the large table in the middle of the Chorrol Mages Guild Library.