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Deus Ex: Human Revolution Hints
Is there another way into Penn's office?
1 of 3: Looking in through the door or window, you'll see that there's a vent cover on the back wall.
2 of 3: Look to the right of the office door to find another vent cover next to a large cardboard box.
3 of 3: Go along the shaft past that vent cover until you find another one on your left, then go through it to enter Penn's office.