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Fallout 3 Hints
(Optional) Sabotage Vault 101.
1 of 7: You'll get this objective when you talk to Butch, who's guarding the corridor near the clinic.
2 of 7: From where Butch is standing, go back downstairs and follow the "REACTOR" signs to find the door to the Vault 101 Sub-Level area.
3 of 7: Go through the door labeled "FILTER ROOM," and then through the door past it.
4 of 7: Turn left and go through another door, then go through yet another door past that.
5 of 7: Go through the doorway on the right and look for the Vault 101 Maintenance Terminal.